![]() ![]() Also, there was no significant difference in the triglyceride concentrations among the groups and no statistically significant differences were seen in the levels of autoantibodies to oxidized LDL (Ox-LDL). ![]() HDL levels essentially did not change among the groups. Again, the combination of Cr and GSE significantly decreased LDL when compared to placebo (p<0.01). The major decrease in cholesterol concentration was in the LDL levels: placebo -3.0% +/- 4, GSE -1.0% +/- 2.0, Cr -14% +/- 4.0, and the combination -20% +/- 6.0. The decrease in the last group was significantly different from placebo (p < 0.01). Over two months, the average percent change +/- SEM in the total cholesterol from baseline among groups was: placebo -3.5% +/- 4, GSE -2.5% +/- 2, Cr -10% +/- 5, and combination -16.5% +/- 3. The four groups of ten subjects received either placebo bid, chromium polynicotinate (Cr) 200 microg bid, grape seed extract (GSE) 100 mg bid, or a combination of Cr and GSE at the same dosage bid. We examined 40 hypercholesterolemic subjects (total cholesterol 210-300 mg/dL) in a randomized, double-blind, placebo-controlled study. Accordingly, natural means to lower cholesterol levels safely would be welcomed. Many drugs lower circulating cholesterol levels, but they are not infrequently associated with severe side effects. Hypercholesterolemia, a significant cardiovascular risk factor, is prevalent in the American population.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |